Dupuytren Contracture Proven Results

Monday, February 8, 2010

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Injectable Collagenase Clostridium Histolyticum for Dupuytren's Contracture

In this randomized, double-blind trial involving 308 patients with Dupuytren's contractures, injections of collagenase clostridium histolyticum were more effective than placebo injections in reducing contractures and restoring range of motion. Adverse effects included tendon rupture in two patients and localized pain and swelling in most patients. (Source: New England Journal of Medicine)
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Results of total aponeurectomy for Dupuytren�s contracture in 61 patients: a retrospective clinical study

Conclusion We suggest that total aponeurectomy is a promising alternative to partial fasciectomy with low risk for a recurrence and slightly increased risk for a nerve lesion. Content Type Journal ArticleCategory Orthopaedic SurgeryDOI 10.1007/s00402-008-0657-zAuthorsA. H�gemann, St.Josefs-Hospital Cloppenburg Department of Traumatology, Hand and Reconstructive Surgery Krankenhausstr.13 49661 Cloppenburg GermanyU. Wolfhard, University of Duisburg�Essen Medical Faculty Duisburg�Essen GermanyD. Kendoff, Hospital for Special Surgery Orthopaedic Department New York USAT. N. Board, Wrightington Hospital and the University of Manchester Manchester UKL. C. Olivier, St.Josefs-Hospital Cloppenburg Department of Traumatology, Hand and Reconstructive Surgery Krankenhausstr....

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